...Retinoic acid binds to all three kinds of retinoid receptors: alpha, beta, and gamma. It is thought that the gamma receptor is the most important in the pathogenesis of acne, and retinoic acid has a very high affinity for gamma receptors. First of all, there is sebum. Sebum itself might be comedogenic, but whether it is or not, it certainly provides the nutrient material for P acnes. The proliferation of this microorganism is the next pathogenic factor. ...»
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«...• Accutane is considered to be breakthrough for acne treatment. It is available in the form of pills or tablets and is said to be great medication that can be taken orally for treating the acne. The ingredient is also called as Isotretinoin....»
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